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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 7.27
Human Site: T45 Identified Species: 10.67
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 T45 W L L R G Q R T C D A S P P W
Chimpanzee Pan troglodytes XP_001143873 959 106437 T45 W L L R G Q R T C D A S P P W
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 A45 W L F R G R R A C D A F P S W
Dog Lupus familis XP_854391 960 106631 A45 W L P R G R R A C D A S P P W
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 S37 R V P S A S G S W L R R G C R
Rat Rattus norvegicus Q924S5 950 105774 S37 R V P S A S G S W L R R G C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382
Chicken Gallus gallus XP_001232112 790 89040
Frog Xenopus laevis Q2TAF8 856 94553 T35 T M R T S V D T P G N M E L V
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 D34 S T M R V S V D T A R N M Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 D37 S L M Q Y C R D R S L R L Q R
Honey Bee Apis mellifera XP_392970 995 112847 V38 S D Y K E L S V H I R P Q F K
Nematode Worm Caenorhab. elegans O44952 971 108188 N34 F A T F S Q R N Q S I L M M K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 R37 V L L G R R V R F C S N S S A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 Q37 P L F K A L S Q I T G W N R R
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 S102 S I L A K D D S T S Q K K D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 66.6 80 N.A. 0 0 N.A. 0 0 6.6 6.6 N.A. 13.3 0 13.3 N.A.
P-Site Similarity: 100 100 73.3 86.6 N.A. 13.3 13.3 N.A. 0 0 13.3 20 N.A. 26.6 6.6 20 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 33.3 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 19 0 0 13 0 7 25 0 0 0 7 % A
% Cys: 0 0 0 0 0 7 0 0 25 7 0 0 0 13 0 % C
% Asp: 0 7 0 0 0 7 13 13 0 25 0 0 0 7 0 % D
% Glu: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 7 % E
% Phe: 7 0 13 7 0 0 0 0 7 0 0 7 0 7 0 % F
% Gly: 0 0 0 7 25 0 13 0 0 7 7 0 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 7 7 7 0 0 0 0 % I
% Lys: 0 0 0 13 7 0 0 0 0 0 0 7 7 0 13 % K
% Leu: 0 44 25 0 0 13 0 0 0 13 7 7 7 7 7 % L
% Met: 0 7 13 0 0 0 0 0 0 0 0 7 13 7 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 7 13 7 0 0 % N
% Pro: 7 0 19 0 0 0 0 0 7 0 0 7 25 19 0 % P
% Gln: 0 0 0 7 0 19 0 7 7 0 7 0 7 13 0 % Q
% Arg: 13 0 7 32 7 19 38 7 7 0 25 19 0 7 25 % R
% Ser: 25 0 0 13 13 19 13 19 0 19 7 19 7 13 0 % S
% Thr: 7 7 7 7 0 0 0 19 13 7 0 0 0 0 0 % T
% Val: 7 13 0 0 7 7 13 7 0 0 0 0 0 0 7 % V
% Trp: 25 0 0 0 0 0 0 0 13 0 0 7 0 0 25 % W
% Tyr: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _